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Development of Falciparum Malaria in a Panamanian Subspecies of Howler Monkey^*

After adaptation to Colombian and then Panamanian Aotus trivirgatus, the Panama II strain of Plasmodium falciparum was infective for Aloutta villosa trabeata Lawrence. Five serial trophozoite passages were demonstrated, with parasitemias reaching 35,000 per mm³; four animals experienced multiple recrudescences, terminating as long as 175 days after inoculation.

Accepted for publication July 9, 1975.

^* Supported in part by the U.S. Army Medical Research and Development Command under Grant No. DADA 17-72C-2031. This is contribution no. 1364 to the Army Research Program on Malaria.