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Amoxycillin in the Treatment of Typhoid Fever in Children^*

Two hundred children with proved typhoid fever were studied. One hundred were treated with amoxycillin and the results were compared with those of 100 treated with chloramphenicol. The clinical and bacteriological response to amoxycillin was satisfactory. No adverse reactions were encountered in this study. This therapeutic trial indicates that amoxycillin is a drug worthy of further evaluation in the treatment of typhoid fever.

Accepted for publication February 15, 1975.

^* Address reprint requests to: Professor J. N. Scragg, Department of Paediatrics and Child Health, University of Natal Medical School, P. O. Box 17039, Congella 4013, Natal, South Africa.