AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 24(5), 1975, pp. 823-826
Copyright © 1975 by The American Society of Tropical Medicine and Hygiene

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The Treatment of Schistosomiasis Mansoni in Murang'a District, Kenya: A Double Blind Controlled Trial of Three Hycanthone Regimens and Oxamniquine

P. H. Rees, H. N. Bowry, J. M. D. Roberts AND J. J. Thuku
Department of Medicine, University of Nairobi, Nairobi, District Hospital, Murang'a, Division of Vector Borne Diseases, Nairobi, and Provincial Medical Headquarters, Central Province, Kenya

In a pilot study designed to find the most suitable drug regimen for the mass treatment of schistosomiasis mansoni, four regimens were found equally effective. Hycanthone 1.5 mg/kg body weight in a single dose was thought to be the most satisfactory regimen in the given situation. The other regimens were oxamniquine 7.5 mg/kg, hycanthone 1.5 mg/kg given on two occasions a week apart, and hycanthone 2.25 mg/kg, all by intramuscular injection.

Accepted for publication December 13, 1974.






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Copyright © 1975 by the American Society of Tropical Medicine and Hygiene.