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Human Mycobacterium Ulcerans Infections Developing at Sites of Trauma to Skin^*

In Zaire, we studied 180 patients with Mycobacterium ulcerans infections and found 14 with a history of antecedent trauma at the site of the lesion (e.g., gunshot and land mine injuries, penetrating wood splinters, and scorpion stings). Two patients developed lesions following hypodermic injections. We believe that trauma is an important mode of transmitting M. ulcerans infections, or of introducing the etiologic agent into the dermis or subcutaneous tissue from superficially contaminated skin.

Accepted for publication February 2, 1974.

^* This investigation was supported in part by American Leprosy Missions, Inc., New York, N. Y., and Grant No. DADA-17-70-G-9318 from the Medical Research and Development Command, U.S. Army, Washington, D. C.

Please address reprint requests to: Wayne M. Meyers, M.D., Ph.D., Leprosy Atelier, Department of Pathology, University of Hawaii School of Medicine, 3675 Kilauea Avenue, Honolulu, Hawaii 96816.

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