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Inhibition of the Immune Response to Pertussis Vaccine during Plasmodium Berghei Yoelii Infection in Mice^*

Mice infected with Plasmodium berghei yoelii responded poorly to pertussis vaccine when administered at peak parasitemia. This was shown by serum agglutinin titers and lack of protection against intracerebral challenge with virulent Bordetella pertussis.

Accepted for publication February 2, 1974.

^* This work was done at the Department of Microbiology and Immunology, University of Montreal, Montreal, Québec and at the Institute of Microbiology and Hygiene of Montreal, Laval-des-Rapides, Québec. A. Tarzaali was supported by a grant from the Canadian International Development Agency.

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