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Am. J. Trop. Med. Hyg., 23(4), 1974, pp. 586-589
Copyright © 1974 by The American Society of Tropical Medicine and Hygiene

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Treatment of Amebic Liver Abscess with Emetine Hydrochloride, Niridazole, and Metronidazole

A Controlled Clinical Trial

D. V. Datta, Samanta A. K. Singh AND P. N. Chhuttani
Division of Hepatic Diseases, Postgraduate Institute of Medical Education and Research, Chandigarh, India

A controlled clinical trial with three amebicidal regimens was undertaken in the treatment of amebic liver abscess. Twenty patients in each of three groups received either niridazole, metronidazole, or emetine hydrochloride combined with chloroquine. Niridazole was found to produce toxic reactions. Metronidazole was ineffective in seven patients and emetine combined with chloroquine was ineffective in one patient.

Accepted for publication December 8, 1973.






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Copyright © 1974 by the American Society of Tropical Medicine and Hygiene.