AJTMH ASTMH Job Mart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 23(4), 1974, pp. 551-559
Copyright © 1974 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Punyagupta, S.
Right arrow Articles by Petchclai, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Punyagupta, S.
Right arrow Articles by Petchclai, B.

Acute Pulmonary Insufficiency in Falciparum Malaria: Summary of 12 Cases with Evidence of Disseminated Intravascular Coagulation

Sompone Punyagupta, Tanomsri Srichaikul, Prawat Nitiyanant AND Bencha Petchclai
Departments of Medicine and Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

Clinical and laboratory results and pathological findings are presented for 12 cases of acute pulmonary insufficiency due to falciparum malaria. Renal and cerebral complications were also seen in all cases. Hematologic studies indicate disseminated intravascular coagulation in all cases, and hemorrhagic diathesis was noted in ten cases. Nine patients died, and intracapillary fibrin clots were seen in internal organs in 2 of 8 postmortems. Disseminated intravascular coagulation is probably an important mechanism causing serious complications, particularly acute pulmonary insufficiency. A high degree of parasitemia, massive intravascular hemolysis, and delay in recognition and treatment of disseminated intravascular coagulation are important in the outcome. The survival of three cases is believed to be the highest reported survival rate of this lethal complication.

Accepted for publication December 21, 1973.




This article has been cited by other articles:


Home page
 JAMAHome page
K. S. Griffith, L. S. Lewis, S. Mali, and M. E. Parise
Treatment of Malaria in the United States: A Systematic Review
JAMA, May 23, 2007; 297(20): 2264 - 2277.
[Abstract] [Full Text] [PDF]

Home page
 Am J Trop Med HygHome page
G. L. GENRICH, J. GUARNER, C. D. PADDOCK, W.-J. SHIEH, P. W. GREER, J. W. BARNWELL, and S. R. ZAKI
FATAL MALARIA INFECTION IN TRAVELERS: NOVEL IMMUNOHISTOCHEMICAL ASSAYS FOR THE DETECTION OF PLASMODIUM FALCIPARUM IN TISSUES AND IMPLICATIONS FOR PATHOGENESIS
Am J Trop Med Hyg, February 1, 2007; 76(2): 251 - 259.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
A. M. Vogt, A. Barragan, Q. Chen, F. Kironde, D. Spillmann, and M. Wahlgren
Heparan sulfate on endothelial cells mediates the binding of Plasmodium falciparum-infected erythrocytes via the DBL1alpha domain of PfEMP1
Blood, March 15, 2003; 101(6): 2405 - 2411.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1974 by the American Society of Tropical Medicine and Hygiene.