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Immunological Properties and Neutralization of Sea Snake Venoms (II)^*

Anthony T. Tu AND Enrique S. Salafranca

The in vitro neutralization capacity of the sea snake antivenin (equine anti-Enhydrina schistosa) manufactured at Commonwealth Serum Laboratories, Melbourne, Australia, was tested against four heterologous venoms. Venoms of four sea snakes used were Praescutata viperina from the Gulf of Thailand, Pelamis platurus from the Pacific coast of Costa Rica, Central America, Laticauda semifasciata from Gato Island, Philippines, and Laticauda laticaudata from Amami Island, Japan. The antivenin effectively neutralized these venoms. Immunoelectrophoretic properties of these four venoms were also investigated and compared with homologous venom from Enhydrina schistosa.

Accepted for publication May 29, 1973.

^* This investigation was supported by NIH grant 5 R01 GM9172 and a Career Development Award 5 R04 GM41786 to A. T. Tu.

SEATO Fellow.