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Am. J. Trop. Med. Hyg., 21(5), 1972, pp. 518-520
Copyright © 1972 by The American Society of Tropical Medicine and Hygiene

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Some new Nitroimidazole Derivatives

Clinical Trials in Amebic Liver Abscess

S. J. Powell AND R. Elsdon-Dew
Amoebiasis Research Unit, Institute for Parasitology, and Department of Medicine, University of Natal, * Durban, South Africa

Clinical trials in amebic liver abscess of three new metronidazole derivatives, nitrimidazine, tinidazole and Ro 7-0207 are reported. While all showed activity to a varying degree, none appeared to be an advance on metronidazole.

Accepted for publication February 23, 1972.


* The Amoebiasis Research Unit is sponsored by the following bodies: The South African Medical Research Council; The Natal Provincial Administration; The University of Natal; The United States Public Health Service (Grant AI 09654-02).






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Copyright © 1972 by the American Society of Tropical Medicine and Hygiene.