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Mattenheimer's Clinical Enzymology—Principles and Applications

by HERMAN MATTENHEIMER, Professor of Biochemistry, Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, Chicago. 179 pages. Ann Arbor Science Publishers Inc., P. O. Box 1425, Ann Arbor, Michigan 48106. 1971. $14.75

The author has condensed an extraordinary amount of information into this rather diminutive book. It is surprising, therefore, that the information is quite lucidly presented in spite of the brevity of the exposition.

Less than a third of the book is devoted to the explanation of basic enzymology and pathways of intermediary metabolism. Building on this foundation, the author relates variations in enzymes of tissue and blood plasma to clinical and genetic disorders. The book serves to introduce the quantitative analysis of tissue enzymes by ultramicro chemical technics, a field pioneered by the author, but relatively little space is devoted to the topic. It is nevertheless apparent that such procedures will soon become routine in clinical laboratories and that needle biopsies will be used to provide information to the clinician not only regarding the anatomic status of an organ but also its functional status.The organization of the book and the detailedtable of contents supplement the index in facilitating the finding of information pertinent to specific disorders.