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Am. J. Trop. Med. Hyg., 21(4), 1972, pp. 473-475
Copyright © 1972 by The American Society of Tropical Medicine and Hygiene

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Hepatitis-Associated (Australia) Antigen in Nigerians

AN ULTRASTRUCTURAL STUDY*

A. Olufemi Williams AND June D. Almeida
Department of Pathology, University of Ibadan, Ibadan, Nigeria, and Department of Virology, Royal Postgraduate Medical School, Hammersmith, London

A series of Australia antigen-positive sera from healthy Nigerians was examined using the electron microscope. One serum was outstanding inasmuch as it contained a vast preponderance of the large 420 A Dane particles. Other sera exhibited the appearance accepted as the usual one in Australia antigen-positive sera. The significance of this variation in proportion of antigen forms is discussed and it is suggested that variations of this type could be of importance in prognosis.

Accepted for publication January 8, 1972.


* Request reprints from Professor A. O. Williams, Department of Pathology, University of Ibadan, University College Hospital, Ibadan, Nigeria.






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Copyright © 1972 by the American Society of Tropical Medicine and Hygiene.