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Am. J. Trop. Med. Hyg., 21(4), 1972, pp. 407-414
Copyright © 1972 by The American Society of Tropical Medicine and Hygiene

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Lymphographic Changes in Regional Lymphatics of Cats Infected with Brugia Malayi*

Adam Ewert, Ronald Balderach{dagger} AND Sabir Elbihari
Department of Microbiology, University of Texas-Medical Branch, Galveston, Texas 77550

Young cats were infected in the hind feet with Brugia malayi in order to localize the parasite in an area where the regional lymphatics could be readily observed. Following injection of contrast material into afferent vessels in infected cats, lymphograms showed a number of vessels not seen in controls. Although changes seen in lymphograms in general correlated well with gross observations following injection of lymphatic-staining dye, occlusion of vessels seen on lymphography were not visible grossly. When these areas of occlusion were examined on dissection, thrombi, which often contained dead worms, were seen. Living worms usually were recovered in a dilated area just distal to a partial or complete occlusion of the vessel.

Accepted for publication March 11, 1972.


* This study was supported by the United States-Japan Cooperative Medical Science Program administered by the National Institutes of Allergy and Infectious Diseases of the National Institutes of Health, Education and Welfare, DHEW Grant No. AI 08260.


{dagger} Present address: Blodgett Memorial Hospital, Grand Rapids, Michigan.







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Copyright © 1972 by the American Society of Tropical Medicine and Hygiene.