AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 20(6), 1971, pp. 964-968
Copyright © 1971 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by McCloud, T. G.
Right arrow Articles by Russell, P. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McCloud, T. G.
Right arrow Articles by Russell, P. K.

Separation of Dengue Strains on the Basis of a Nonstructural Antigen

Thomas G. McCloud, Robert D. Cardiff, Walter E. Brandt, Dumrong Chiewsilp AND Philip K. Russell
Department of Virus Diseases, Walter Reed Army Institute of Research, Washington, D. C. 20012

Intratypic variation of the nonstructural soluble complement-fixing (SCF) antigens of dengue-1 strains (Hawaii and TH-Sman) and dengue-2 strains (New Guinea C and TH-36) were examined by immunological and biophysical techniques. The SCF antigen of Hawaii could be separated from that of TH-Sman by subtle differences in CF cross reactions but by distinct differences in their relative mobilities when tested by disc-gel electrophoresis. SCF antigens of dengue-2 strains could not be distinguished by any of the methods used. We suggest that the SCF antigen is responsible for the strain variation observed in the two dengue-1 strains.

Accepted for publication June 2, 1971.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1971 by the American Society of Tropical Medicine and Hygiene.