HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Williams, J. F. Articles by Oriol, R. Search for Related Content PubMed PubMed Citation Articles by Williams, J. F. Articles by Oriol, R. Pubmed/NCBI databases Substance via MeSH

Evaluation of Purified Lipoprotein Antigens of Echinococcus Granulosus in the Immunodiagnosis of Human Infection

J. F. Williams^*, Miguela V. Pérez Esandi AND R. Oriol

A purified antigenic fraction of sheep hydatid fluid containing two major lipoprotein components was evaluated in hemagglutination, immunoelectrophoretic, and skin hypersensitivity tests for the diagnosis of 91 cases of human hydatidosis. Most of the serological reactors could be detected by this fraction, though a significant proportion reacted with other components of sheep hydatid fluid that had been eliminated during the fractionation procedure. About 80% of the patients had positive immediate skin reactions after the inoculation of 1.5 µg protein antigen, and there was little evidence of nonspecific reactivity. The relevance of these findings to current problems of immunodiagnosis of hydatid disease was discussed.

Accepted for publication February 17, 1971.

^* Present address: Department of Microbiology and Public Health, Michigan State University, East Lansing, Michigan 48823.

Present address: Médicine Expèrimentale, Collège de France, Paris V^e, France.