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Am. J. Trop. Med. Hyg., 20(3), 1971, pp. 502-505
Copyright © 1971 by The American Society of Tropical Medicine and Hygiene

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Australia/SH Antigen and Immunoglobulins in an Epidemic of Viral Hepatitis

A. N. Malaviya, S. K. Sama, K. Ramachandran, P. C. Gandhi AND B. N. Tandon
Departments of Medicine and Social and Preventive Medicine, All-India Institute of Medical Sciences, New Delhi-16, India

In an epidemic of viral hepatitis caused by polluted water, 97 of 981 persons examined showed evidence of hepatitis. None of these 97 persons gave evidence of infection with Australia/SH antigen. In 26 persons randomly selected from those with hepatitis, immunoglobulin (IgG and IgM) levels were significantly elevated. We concluded that the causative agent of this short-incubation period hepatitis, which resembled infectious hepatitis, was antigenically different from Australia/SH antigen.

Accepted for publication September 17, 1970.






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Copyright © 1971 by the American Society of Tropical Medicine and Hygiene.