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Carrión's Disease

I. Studies on Plants Claimed to be Reservoirs of Bartonella bacilliformis¹

In testing the hypothesis that certain euphorbiaceous plants may be the reservoirs of Carrión's disease in Peru, the following results were obtained:

1. Cultures of latex of Jatropha macrantha and J. basiacantha from the Peruvian verruga zone were completely negative for Bartonella bacilliformis.

2. Attempts to infect seedlings of both plants with cultures failed completely.

3. The growth of B. bacilliformis in vitro is inhibited by the presence of latex in amounts greater than 1 part in 50.

4. There appears to be little likelihood that these plants could serve as the disease reservoirs.

¹ Studies carried out in the Division of Entomology and Economic Zoology, University of Minnesota, under a fellowship of the John Simon Guggenheim Memorial Foundation.

The author desires to express his most sincere thanks to Dr. Clarence E. Mickel, Chief of the Division of Entomology and Economic Zoology; to Dr. G. B. Fairchild, Professor of Medical Entomology, under whose immediate direction the work was done; and to many others at the University for their kind and helpful cooperation.