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The Present Status of the Chemotherapy of Toxoplasmosis

Since the discovery of Toxoplasma gondii as a cause of human disease, a number of investigators have attempted to find chemotherapeutic agents effective against this parasite. These efforts are continuing and some progress has been and is being made. For that reason I have chosen to summarize this work up to the present time as my contribution to this symposium on toxoplasmosis.

We consider it important to find effective chemotherapeutic agents, for, as diagnostic procedures improve and become more universally used, an increasingly large number of cases of disease will be found at an early stage. Admittedly, it is unlikely that any drug could do more than arrest the progress of the subacute or chronic congenital infection; however, it is reasonable to suppose that some congenital cases may be recognized at a stage sufficiently early to be amenable to treatment. Certainly, effective drugs would be important also in acute infections acquired after birth in either children or adults if we can recognize these infections sufficiently early in the course of the disease.

¹ 874 Union Avenue, Memphis 3, Tennessee.

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