AJTMH HINARI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 19(6), 1970, pp. 996-1000
Copyright © 1970 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Akpom, C. A.
Right arrow Articles by Warren, K. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Akpom, C. A.
Right arrow Articles by Warren, K. S.

Comparison of Formation of Granulomata around Eggs of Schistosoma Mansoni in the Mouse, Guinea Pig, Rat, and Hamster*

C. Amechi Akpom, M. F. Abdel-Wahab{dagger} AND Kenneth S. Warren{ddagger}
Departments of Preventive Medicine and Medicine, Case Western Reserve University School of Medicine, and University Hospitals, Cleveland, Ohio 44106

A model of the immunopathology of the granulomatous response to Schistosoma mansoni eggs (a form of delayed hypersensitivity) has been established in the mouse. For certain types of investigation of granuloma formation, however, other species of laboratory animals may be preferable. Thus eggs of S. mansoni were injected into the microvasculature of the lungs of rats, guinea pigs, and hamsters as well as mice. The response of the rodents was temporally and qualitatively similar, although the lesions differed in size.

Accepted for publication May 5, 1970.


* This investigation was supported in part by grants from The Rockefeller Foundation, USPHS grant No. FR-05410-08, and the US-Japan Cooperative Medical Science Program administered by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (grant No. AI31814-03).


{dagger} On leave from the Department of Clinical Tropical Medicine, Cairo University, Cairo, United Arab Republic.


{ddagger} Holder of USPHS Career Development Award AI 08163-03.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1970 by the American Society of Tropical Medicine and Hygiene.