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Studies on Trachoma

VII. Isolation of a Mixture of Type 1 and Type 2 Trachoma Strains from a Child in Saudi Arabia^*

A strain of trachoma isolated from a 3-year-old girl in Saudi Arabia initially showed antigenic characteristics of both types 1 and 2 by toxin-protection tests in mice and by fluorescent-antibody tests. Pure types 1 and 2 were separated from the parent strain in four experiments with limiting dilutions in eggs. We concluded that this strain was therefore a mixture, rather than a hybrid; there is no evidence from this laboratory nor in published reports that either phenomenon has been reported previously.

Accepted for publication December 10, 1969.

^* This study was supported by the Arabian American Oil Company and by grants to the Harvard School of Public Health from the National Institutes of Health (General Research Support Grant, FR-5446-04, and the National Institutes of Allergy and Infectious Diseases, AI-06251-02).