AJTMH Tropical Medicine and Hygiene News
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 19(5), 1970, pp. 815-820
Copyright © 1970 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Aljeboori, T. I.
Right arrow Articles by Ivey, M. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Aljeboori, T. I.
Right arrow Articles by Ivey, M. H.

Toxocara Canis Infections in Baboons

II. Distribution of Larvae and Histopathologic Responses*

T. I. Aljeboori{dagger}, C. Stout AND M. H. Ivey
Department of Parasitology and Laboratory Practice and Department of Pathology, University of Oklahoma Medical Center, Oklahoma City, Oklahoma 73104

This is the second of a two-part report of an investigation to determine the response of baboons to Toxocara canis. The first report dealt with the white cell, serum protein, and antibody responses of infected baboons. The present paper describes the gross findings at autopsy, distribution of larvae, and the associated histopathologic response. Estimates of the number of larvae in the liver, lungs, brain, and heart were obtained by digestion of portions of these organs from four animals. In every instance greater numbers of larvae per gram of organ occurred in the liver. However, in three of the animals, roughly the same number of larvae were recovered per gram of lung tissue. Histologic studies suggested that the invading larvae migrated extensively through the liver during the first week of infection, producing considerable inflammation and necrosis, which was almost completely resolved by the 3rd week, coinicident with the height of intra-alveolar hemorrhage and edema in the lungs. Although this investigation was terminated prematurely because of an epidemic of tuberculosis, analysis of the various comparable data showed no apparent differences between two pairs of tubercular and nontubercular animals.

Accepted for publication January 19, 1970.


* Supported in part by grant HE08275, National Heart Institute, and grant AI09442-01, National Institutes of Health.


{dagger} Present address: Department of Bacteriology and Parasitology, Baghdad University College of Medicine, Baghdad, Iraq.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1970 by the American Society of Tropical Medicine and Hygiene.