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Correspondence

12 February 1970

To the Editor

I hesitate to embroider the remarks of so distinguished a worker as Dr. Fred L. Soper, but he brings up a point in his letter in the May 1969 issue of the Journal to which I would like to make a small contribution.

He wrote that the most sensitive index of occult yellow fever is viscerotomy and liver examination. In using such histological material as an epidemiological tool, yellow fever researchers pioneered an approach the value of which is still not appreciated by many workers in the tropics.

Today, with rapid communications, pathologists in the United States or Europe can give an opinion on material from New Guinea, for example, in a matter of days. In the tropics, the cause of death in many patients still remains a mystery and the fullest use should be made of postmortem material to elucidate this cause.