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Am. J. Trop. Med. Hyg., 19(4), 1970, pp. 692-694
Copyright © 1970 by The American Society of Tropical Medicine and Hygiene

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Lassa Fever, a New Virus Disease of Man from West Africa

IV. Electron Microscopy of Vero Cell Cultures Infected with Lassa Virus*

R. W. Speir, O. Wood, H. Liebhaber AND S. M. Buckley
Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510

Vero cell cultures infected with Lassa virus contained pleomorphic particles of variable size, with surface projections and with one or more electron-dense granules lying within the particles. These particles resemble those previously described in cell cultures infected with lymphocytic choriomeningitis virus, Machupo virus, and Tacaribe virus.

Accepted for publication March 28, 1970.


* This investigation was supported by The Rockefeller Foundation and by the United States-Japan Cooperative Medical Science Program administered by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, Department of Health, Education, and Welfare, under Grant No. 1-R22-AI-08215-01A1.




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T. P. Monath, V. F. Newhouse, G. E. Kemp, H. W. Setzer, and A. Cacciapuoti
Lassa Virus Isolation from Mastomys natalensis Rodents during an Epidemic in Sierra Leone
Science, July 19, 1974; 185(4147): 263 - 265.
[Abstract] [PDF]




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Copyright © 1970 by the American Society of Tropical Medicine and Hygiene.