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Am. J. Trop. Med. Hyg., 19(4), 1970, pp. 610-612
Copyright © 1970 by The American Society of Tropical Medicine and Hygiene

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Niclosamide* Treatment of Cestodiasis

Clinical Trials in the United States

David R. Perera, Karl A. Western AND Myron G. Schultz
Parasitic Disease Drug Service, Parasitic Diseases Branch, Epidemiology Program, National Communicable Disease Center (NCDC), Health Services and Mental Health Administration, U. S. Public Health Service, Atlanta, Georgia 30333

Niclosamide was given to 81 patients with tapeworm infection. Forty-seven patients received adequate follow-up, and 46 were cured; 17 of these had previously shown no improvement with quinacrine. Results indicate that niclosamide is a safe, simple, and effective agent against infection with Taenia saginata, Diphyllobothrium latum, and Hymenolepis nana.

Accepted for publication December 4, 1969.


* Niclosamide (Yomesan) is available, for investigational use only, from the Parasitic Disease Drug Service, Parasitic Diseases Branch, Epidemiology Program, National Communicable Disease Center, Atlanta, Georgia 30333.







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