AJTMH Tropical Medicine and Hygiene News
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 19(2), 1970, pp. 289-291
Copyright © 1970 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hillyer, G. V.
Right arrow Articles by Hernández-Morales, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hillyer, G. V.
Right arrow Articles by Hernández-Morales, F.

Evidence of Transplacental Passage of Specific Antibody in Schistosomiasis Mansoni in Man*

George V. Hillyer{dagger}, Rodrigo Menéndez-Corrada, Rosa Lluberes AND Federico Hernández-Morales
General Medical Research Laboratory, Veterans Administration Center (151), GPO Box 4864, San Juan, Puerto Rico 00936

Transplacental passage of specific antibodies from mother to neonatal infant was demonstrated in Schistosoma mansoni infections in man. This passage of antibody was demonstrated by the circumoval precipitin method, the Ouchterlony double-diffusion method with adult worm and cercarial extracts of S. mansoni, and by the cercarial slide-flocculation method. Immunoglobulin levels between mothers and their infants were compared by simple radial immunodiffusion. Levels of immunoglobulin G of mothers and their infants were similar; however, no immunoglobulin A was detected in the serum from the neonatal infants, and only three of 16 infants had measurable amounts of immunoglobulin M by the methods used. We believe this to be presumptive evidence that the transplacental passage of specific antibodies from mothers to their neonatal infants in S. mansoni infections is due to serum IgG.

Accepted for publication July 1, 1969.


* Presented, in part, at the Seventeenth Annual Meeting of The American Society of Tropical Medicine and Hygiene, 30 October-1 November 1968, Atlanta, Georgia.


{dagger} Department of Microbiology, The University of Chicago, 939 East 57th Street, Chicago, Illinois 60637. Trainee, United States Public Health Service Training Grant No. AI-00331.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1970 by the American Society of Tropical Medicine and Hygiene.