AJTMH ASTMH MEMBERSHIP INFORMATION: astmh@astmh.org
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 18(3), 1969, pp. 346-350
Copyright © 1969 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Baerg, D. C.
Right arrow Articles by Young, M. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Baerg, D. C.
Right arrow Articles by Young, M. D.

Sporozoite Transmission of Plasmodium Vivax to Panamanian Primates*

David C. Baerg, James A. Porter, Jr.{dagger} AND Martin D. Young
Gorgas Memorial Laboratory, P. O. Box 2016, Balboa Heights, Canal Zone

Anopheles albimanus mosquitoes transmitted blood-induced Plasmodium vivax infection from three night monkeys, Aotus trivirgatus, to three other night monkeys and to a Panamanian marmoset, Saguinus geoffroyi. Mosquito-transmissions of the malaria also were successful from one black spider monkey, Ateles fusciceps, to two other black spider monkeys. Prepatent periods ranged from 14 to 29 days and patent periods from 19 to 37 days. Plasmodium vivax in S. geoffroyi developed less than 10 parasites per cmm in contrast to maxima of 42,850 and 8,390 per cmm in A. trivirgatus and A. fusciceps on primary infection. Relapse occurred in one A. trivirgatus and in one A. fusciceps after subpatent intervals of 27 and 4 days. The relapse infections were patent for 29 and 24 days and reached maxima of 15,420 and 15,470 parasites per cmm. Mosquitoes were infected from feeding upon each A. trivirgatus and one A. fusciceps. This report of mosquito-transmissions of P. vivax infection to Panamanian primates appears to be the first of sporozoite-induced human malaria in monkeys.


* Research sponsored by the U. S. Army Medical Research and Development Command, under Grant No. DADA 17-68-G-9264. This is paper No. 567 from the Army Research Program on Malaria.


{dagger} Present address: Veterans Administration, Edward Hines Jr. Hospital, RILAMSAT, Bldg. 189a, Hines, Illinois 60141.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1969 by the American Society of Tropical Medicine and Hygiene.