HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Punyagupta, S. Articles by Nye, S. W. Search for Related Content PubMed PubMed Citation Articles by Punyagupta, S. Articles by Nye, S. W.

Radiculomyeloencephalitis Associated with Eosinophilic Pleocytosis

Report of Nine Cases^*

Sompone Punyagupta, Chaya Limtrakul, Prakit Vichipanthu, Chul Karnchanachetanee AND Sylvanus W. Nye

Eosinophilic encephalitis with manifestations of headache, paresthesia, and paralysis of cranial nerves VI and VII is well recognized in Thailand, but radiculomyeloencephalitis with eosinophilic pleocytosis has not been reported. In nine cases, six men and three women, there were sharp, shooting pains of the trunk and limbs. Flaccid paralysis and impairment of superficial sensation occurred. Cerebrospinal fluid showed between 92 and 880 white cells per cmm, 24 to 55% eosinophils in all cases, and increased protein in eight. Two patients died suddenly. The autopsy in one case showed a long necrotic, hemorrhagic track in the spinal cord and perivascular infiltration of plasma cells and eosinophils in the cord and midbrain. Parasites were not detected. The parasite causing spinal-cord involvement is most likely not Angiostrongylus cantonensis, which produces typical eosinophilic meningitis.

^* This work was supported by the Pacific Research Section, National Institute of Allergy and Infectious Diseases, United States Public Health Service, Honolulu, Hawaii, and the United States Army Medical Component, South East Asia Treaty Organization, Bangkok, Thailand. Manuscript preparation was supported in part by U. S. Army Medical Research and Development Command, Contract No. DA DA 17-67-C-0022 with the University of North Carolina.

Please address requests for reprints to Dr. Punyagupta or Dr. Nve.

Ubol Provincial Hospital, Ubol, Thailand.

Prachinburi Provincial Hospital, Prachinburi, Thailand.

Department of Pathology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina. Formerly, Captain (MC) U.S.A.F. Geographic Pathology Division, Armed Forces Institute of Pathology assigned to SEATO Medical Research Laboratory, Bangkok, Thailand.