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An apparent case of chloroquine-resistant falciparum malaria was reported from eastern coastal Brazil from the state of Espírito Santo some 550 kms northeast of Rio de Janeiro. This constitutes a new endemic area. The patient was successfully treated with a combination of quinine sulfate, sulfadiazine, and pyrimethamine.
* Partially supported by National Institutes of Health Training Grant 5 TI Al-0128.
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