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Am. J. Trop. Med. Hyg., 16(6), 1967, pp. 729-734
Copyright © 1967 by The American Society of Tropical Medicine and Hygiene

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Circumoval Antibodies

Measurement during Treatment of Experimental Schistosomiasis*

Marta Cancio, Amina Rivera De Sala, Gustavo Ramírez De Arellano AND Rafael Rodríguez-Molina
General Medical Research Laboratories, Veterans Administration, San Juan, Puerto Rico

The hypothesis that the mean length of the precipitates produced in the circumoval precipitin reaction (COP) depends on the mean amount of antiegg antibody present in the serum of animals or man infected with the parasite S. mansoni was tested during the course of infection, and of treatment and treatment-withdrawal, in experimental schistosomiasis. Results indicate that measurement of the mean length of the circumoval precipitates may be useful in the evaluation of drugs against infection with S. mansoni.


* Read at the 15th Annual Meeting of The American Society of Tropical Medicine and Hygiene, 1 November 1966, San Juan, Puerto Rico.






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Copyright © 1967 by the American Society of Tropical Medicine and Hygiene.