AJTMH HINARI
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am. J. Trop. Med. Hyg., 16(3), 1967, pp. 339-347
Copyright © 1967 by The American Society of Tropical Medicine and Hygiene

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Brandt, W. E.
Right arrow Articles by Hetrick, F. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Brandt, W. E.
Right arrow Articles by Hetrick, F. M.

Production and Characterization of Arbovirus Antibody in Mouse Ascitic Fluid

Walter E. Brandt*, Edward L. Buescher* AND Frank M. Hetrick{dagger}

Specific high-titered arbovirus CF antibody was obtained in mouse ascitic fluid. Primary and secondary immunization consisting of multiple closely spaced injections produced an antibody response similar to that found after one primary and one secondary injection, but resulted in higher-titered yet similarly specific reagents. Subcutaneous inoculation was shown to be more effective than intraperitoneal inoculation for primary immunization, whereas the reverse was true for secondary immunization. CF and HI antibody in hyperimmune ascitic fluid was found only in the 7S gamma G-immunoglobulin region. AC activity was found in the 19S portion of the gamma globulin region of unheated ascitic fluid; it was heat labile when isolated from 7S gamma G-immunoglobulins and heat stable in their presence. Nonspecific inhibitors in the HI test were shown to be lipoproteins that were not associated with 19S or 7S globulins.


* Department of Virus Diseases, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D. C. 20012.


{dagger} Department of Microbiology, University of Maryland, College Park, Maryland 20740.




This article has been cited by other articles:


Home page
 J. Gen. Virol.Home page
B. E. Dewi, T. Takasaki, and I. Kurane
Peripheral blood mononuclear cells increase the permeability of dengue virus-infected endothelial cells in association with downregulation of vascular endothelial cadherin
J. Gen. Virol., March 1, 2008; 89(3): 642 - 652.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
M. J. Vincent, A. J. Sanchez, B. R. Erickson, A. Basak, M. Chretien, N. G. Seidah, and S. T. Nichol
Crimean-Congo Hemorrhagic Fever Virus Glycoprotein Proteolytic Processing by Subtilase SKI-1
J. Virol., August 15, 2003; 77(16): 8640 - 8649.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
D. Francy, N Karabatsos, D. Wesson, C. Moore Jr, J. Lazuick, M. Niebylski, T. Tsai, and G. Craig Jr
A new arbovirus from Aedes albopictus, an Asian mosquito established in the United States
Science, December 21, 1990; 250(4988): 1738 - 1740.
[Abstract] [PDF]

Home page
 ScienceHome page
D. M. Watts, S. Pantuwatana, G. R. DeFoliart, T. M. Yuill, and W. H. Thompson
Transovarial Transmission of LaCrosse Virus (California Encephalitis Group) in the Mosquito, Aedes triseriatus
Science, December 14, 1973; 182(4117): 1140 - 1141.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1967 by the American Society of Tropical Medicine and Hygiene.