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Studies on Guaroa Virus

I. Virus Characteristics^*

Richard W. March AND Frank M. Hetrick

Guaroa virus is sensitive to ether and deoxycholate, its replication in cell culture is not inhibited by 5-iodo-2'-deoxyuridine, and it is both pH and heat labile. The virus produces cytopathology in certain cell cultures of human and bovine origin and has a rapid growth rate in bovine lymph-node cell cultures.

^* Supported in part by Surgeon General Office Contract DA-49-193-MD-2476, Contribution No. 3838 of the Maryland Agricultural Experiment Station, Department of Veterinary Science.

Present Address: Virus & Disease Modification Section, Viral Leukemia & Lymphoma Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014.

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