AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 15(4), 1966, pp. 656-657
Copyright © 1966 by The American Society of Tropical Medicine and Hygiene

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Mechanisms of Death and Tissue Injury in Malaria

by M. A. AL-DABAGH, B.V.Sc. (Cairo), M.Sc. (U.S.), PH.D. (London), Assistant Professor of Parasitology, Medical College, Baghdad University, with a foreword by P. C. C. GARNHAM, C.M.G., M.D., D.Sc., F.R.S., Professor of Protozoology, London School of Hygiene and Tropical Medicine, Lond. vi + 240 pages, illustrated. Shafik Press, Baghdad. 1966

Clay G. Huff
Naval Medical Research Institute Bethesda, Maryland

This monograph is a study in depth of the pathologic action of malaria parasites on the tissues of the host. The experimental work is upon avian malaria and the findings are discussed in reference to the published literature dealing with this subject and, in addition, to the literature on malaria in man and in other primates.

In part one the role of ten conditions associated with malaria is discussed and evaluated. In the following brief summary of this section these ten conditions are italicized. No irritative or pathologic effect of haemozoin is believed to be demonstrated except when it is deposited in some vital organ. In spite of the experimental evidence favoring anoxia as a possible cause of death, its role in causing death has yet to be proved. The striking similarities between the pathological and clinical features of acute malarial infections and secondary shock in man and animals are pointed out.







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Copyright © 1966 by the American Society of Tropical Medicine and Hygiene.