HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Healy, G. R. Articles by Gleason, N. N. Search for Related Content PubMed PubMed Citation Articles by Healy, G. R. Articles by Gleason, N. N.

Studies on the Pathogenicity of Various Strains of Entamoeba Histolytica after Prolonged Cultivation, with Observations on Strain Differences in the Rats Employed

Attempts to utilize the rat cecal scoring technique of Neal to measure the invasiveness of strains of Entamoeba histolytica gave inconsistent results when Sherman strain rats were used. Results with Wistar rats were more consistent.

Two strains of E. histolytica, one in culture for 11 years and another in culture for 4 years, were still as highly infective and invasive as were four strains recently isolated from cases of symptomatic amebiasis.

Strain F22 originally isolated from an amebic abscess of the brain showed diminished infectivity and invasiveness. Its infectivity and invasiveness were restored to a level comparable to recently isolated strains when organisms were passed rapidly through rats and culture.

^* Communicable Disease Center, Public Health Service, U. S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333.