HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ivey, M. H. Search for Related Content PubMed PubMed Citation Articles by Ivey, M. H.

Immediate Hypersensitivity and Serological Responses in Guinea Pigs Infected with Toxocara Canis or Trichinella Spiralis^*

Schultz-Dale tests with ilea from guinea pigs infected with 100, 500, 1000 or 2100 Toxocara eggs for 4, 6 or 10 weeks indicated increased sensitization with increased numbers of worms and duration of infection. Schultz-Dale tests detected variable, but striking, quantitative differences between stage-specific antigens and heterologous antigens of Toxocara, Ascaris, and Trichinella. Desensitization tests pointed towards means of identifying antigens in other parasites that are common to Toxocara. Tests for passive cutaneous anaphylaxis correlated with Schultz-Dale tests, but hemagglutination and gel diffusion tests did not.

^* Portions of this study were supported by NIH Special Fellowship ESP-5358, NIAID E-4722, and a University of Missouri United Fund Grant. The author is grateful to Drs. Paul Beaver and Rodney Jung of Tulane University School of Medicine for their interest and support during the tenure of the fellowship in 1962–63.