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Am. J. Trop. Med. Hyg., 14(4), 1965, pp. 605-609
Copyright © 1965 by The American Society of Tropical Medicine and Hygiene

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Chromium51 Red Cell Half-Life in Severe Iron Deficiency Anemia*

Z. Farid, J. H. Nichols, A. R. Schulert AND S. Bassily
Medical and Biochemistry Department, U. S. Naval Medical Research Unit No. 3, Cairo, Egypt, U. A. R., and Division of Nutrition and Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee

The relationship between Cr51 red cell half-life, degree of iron deficiency anemia, and intestinal blood loss was studied in twenty-seven patients and the half-life found to be shortened in all patients with hemoglobin values under 6.5 g per 100 ml, irrespective of intestinal blood loss. Treatment of the anemia corrected the half-life. Sequestration of the iron-depleted red cells by the enlarged spleen was demonstrated in two severely anemic patients.


* The opinions and assertions contained herein are the private ones of the authors and are not to be construed as official or reflecting the views of the Navy Department, the naval service at large, or the Egyptian Ministry of Public Health.






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Copyright © 1965 by the American Society of Tropical Medicine and Hygiene.