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Immunodiffusion Studies on Paragonimiasis^*

Mariano G. Yogore, Jr., Robert M. Lewert AND Eloisa D. Madraso

By micro-Ouchterlony and micro-immunoelectrophoretic technics utilizing antisera from humans and cats infected with Paragonimus westermani, from two to five precipitating systems were found, depending on the infected individual. All precipitinogens detected in a secretory-excretory antigen were also present in the somatic extract of the adult worms.

The same two precipitins were detected in all four human antisera studied. Two to four precipitins, not identical to those in human infections, were found in common in five of six cat antisera. In one cat antiserum, two precipitins of apparent identity with the human precipitins were detected.

^* These investigations were conducted under the sponsorship of the Commission of Parasitic Diseases of the Armed Forces Epidemiological Board and supported by the U. S. Army Medical Research and Development Command, Department of the Army, by contract DA-49-193-MD-2320, and by National Institutes of Health grant, List No. RF-9-61, Allotment No. 10001-03, by arrangement with and support of the authorities of the University of the Philippines, Quezon City, Philippines.

Department of Parasitology, Institute of Hygiene, University of the Philippines.

Department of Microbiology, University of Chicago, Illinois.