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Application of Serology to the Epidemiology of Amebiasis

The incidence of anti-amebic precipitins was determined in sixteen different populations. These included hospitalized patients in Durban and blood donors of various racial groups in Durban, Johannesburg and Capetown. Correlation was found between the prevalence of antibodies and the incidence of invasive amebiasis. The observation indicates the value of the serological approach in determining the importance of Entamoeba histolytica as a pathogen in populations and areas. Its objectivity gives it an additional advantage over stool survey.

^* The Amoebiasis Research Unit is sponsored by the following bodies: The South African Council for Scientific and Industrial Research, The University of Natal, The Natal Provincial Administration, and The United States Public Health Service (grant AI 01592).