HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Degowin, R. L. Articles by Powell, R. D. Search for Related Content PubMed Articles by Degowin, R. L. Articles by Powell, R. D.

Drug Resistance of a Strain of Plasmodium Falciparum from Malaya^*

Richard L. Degowin AND Robin D. Powell

Investigations conducted with volunteers infected with a strain of Plasmodium falciparum from Malaya disclosed that the asexual erythrocytic forms of this strain were resistant to usually effective doses of chloroquine, hydroxychloroquine, amodiaquine, mepacrine, proguanil, and pyrimethamine. Radical cure of infections with this strain was effected in 12 of 13 volunteers treated with 10 grains of quinine sulfate thrice daily for 7 or 10 days.

^* These studies were supported by the Medical Research and Development Command, Office of the Surgeon General, Department of the Army, under Contract DA-49-193-MD-2413 with the University of Chicago. An abstract that concerns, in part, studies described in this report has been published.¹

Captain, Medical Corps, United States Army, and Research Associate, Department of Medicine, University of Chicago.

Assistant Professor, Department of Medicine, University of Chicago.

This article has been cited by other articles:

				C. D. Fitch Plasmodium falciparum in Owl Monkeys: Drug Resistance and Chloroquine Binding Capacity Science, July 17, 1970; 169(3942): 289 - 290. [Abstract] [PDF]

				Q. M. Geiman, W. A. Siddiqui, and J. V. Schnell Plasma Replacement for in vitro Culture of Plasmodium klowlesi Science, September 2, 1966; 153(3740): 1129 - 1130. [Abstract] [PDF]