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California Encephalitis Virus Infection: A Case Report^*

Donald T. Quick, Arthur G. Smith, Arthur L. Lewis, Gladys E. Sather^|| AND William McD. Hammon^¶

A case of severe encephalitis in a previously healthy 12-year-old girl was associated with a diagnostic rise in antibodies representing recent infection with a California group arbovirus. This case is the first report of human disease associated with this infection since the original studies in California and is the initial report of a case from Florida.

^* These studies were supported by Public Health Service Research Grant AI-05504 from the National Institute of Allergy and Infectious Diseases to the Florida State Board of Health.

Studies at the University of Pittsburgh were conducted under the sponsorship of The Commission on Viral Infections, Armed Forces Epidemiology Board, and were supported in part by the Research and Development Division, Office of the Surgeon General, Department of the Army, under Contract Number DA-49-193-MD-2042, and in part by Public Health Service Research Grant AI-02686 from the National Institute of Allergy and Infectious Diseases.

Medical Epidemiologist, U. S. Public Health Service, Communicable Disease Center, Atlanta, Georgia, on assignment to the Florida State Board of Health.

Staff Pediatrician, The Mease Hospital and Clinic, Dunedin, Florida.

Virologist at the Encephalitis Research Center.

^|| Research Associate, Department of Epidemiology and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

^¶ Professor of Epidemiology and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

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