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Chloroquine-Resistant Strain of Plasmodium Falciparum from Khao Mai Khaeo, Thailand^*

Udaya Sandhinand, Katchrinnee Pinswasdi AND James M. Neely

A naturally infected case of chloroquine-pyrimethamine resistant Plasmodium falciparum malaria acquired in Khao Mai Khaeo, Cholburi Province, Thailand, is described. This strain of P. falciparum was inoculated into a healthy volunteer. The artificially induced infection also proved to be resistant to chloroquine and pyrimethamine. Radical cure was effected by quinine therapy.

^* The opinions and conclusions expressed are those of the authors as individuals, and are not the offical positions of the Surgeon General, United States Army, or the United States Army Medical Service.

Malariologist, Malaria Research Project.

Biochemist, Malaria Research Project.

1st Lt., MSC, Assistant Chief, Department of Medical Entomology.