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Dynamic Pathology, Structural and Functional Mechanisms of Disease

by MAURICE M. BLACK, M.D., Professor of Experimental Pathology, New York Medical College, New York, N. Y.; Attending Pathologist, Flower and Fifth Avenue Hospitals, New York, N. Y., and BERNARD M. WAGNER, M.D., Professor and Chairman, Department of Pathology, New York Medical College, New York, N. Y.; Pathologist, Flower and Fifth Avenue Hospitals, New York, N. Y. 296 pages, illustrated. The C. V. Mosby Co., St. Louis, Mo. 1964. $8.00

This book deals with the interrelationships between the morphological, biochemical and genetic aspects of the homeostatic mechanisms in man.

The first part includes a review of these homeostatic mechanisms in a "steady state." The close interdependence of ultrastructural organization, chromosomal mechanics and biochemical function is illustrated by a description of many inborn errors of metabolism. The vascular and endocrinological homeostasis, the function of liver and kidney, and the importance of the reticulo-endothelial system and the connective tissue are further delineated. The functions of the lungs, the nervous system, the muscle mass and the bones are not discussed.

The second part is a survey of cancer, radiation, deficiency diseases and aging as challengers to the homeostatic mechanisms.

A list of recent references and of pertinent motion pictures is given at the end of each chapter.