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Am. J. Trop. Med. Hyg., 14(2), 1965, pp. 304-308
Copyright © 1965 by The American Society of Tropical Medicine and Hygiene

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Arthropod-Borne Encephalitis Viruses in Northeastern South America

II. A Serological Survey of Northeastern Venezuela*

A. H. Jonkers, W. G. Downs, L. Spence AND T. H. G. Aitken
University of the West Indies, Trinidad Regional Virus Laboratory, P. O. Box 164, Port-of-Spain, Trinidad, W.I.

A total of 287 sera collected from children under 15 years (104) and adults residing in eight communities in Monagas State, Venezuela, was examined for presence of antibodies to arthropodborne viruses by hemagglutination-inhibition and neutralization tests.

No immunity to eastern and western equine encephalitis viruses was encountered, but, with the exception of Maturín, each community had some adults who were immune to Venezuelan equine encephalitis virus. Only three sera from adults were found to neutralize Mayaro. No evidence of recent activity of yellow fever and dengue type 2 viruses was discovered. Eight sera neutralized Ilhéus but no other group B agent used, and two sera neutralized St. Louis encephalitis virus only. Neutralization test results with a Caraparu-like agent, TRVL 34053-1, indicate that infections with this or a closely related agent have occurred occasionally. In each community there were some sera that neutralized Cache Valley virus. Limited tests with a Manzanilla antigen gave negative results.


* The studies and observations on which this paper is based were conducted with the support and under the auspices of the Governments of Trinidad and Tobago, Jamaica, British Guiana and the Eastern Caribbean Territories, the Department of Technical Cooperation of the United Kingdom Government and The Rockefeller Foundation.






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Copyright © 1965 by the American Society of Tropical Medicine and Hygiene.