AJTMH Transactions of the Royal Society of Tropical Medicine and Hygiene
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Am. J. Trop. Med. Hyg., 13(3), 1964, pp. 396-401
Copyright © 1964 by The American Society of Tropical Medicine and Hygiene

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Prophylaxis and Therapy of Amebiasis and Shigellosis with Iodochlorhydroxyquin*

Lawrence M. Gholz{dagger} AND Walter L. Arons{ddagger}
Public Health Unit, Sonoma State Hospital, Eldridge, California, and the Department of Medicine, Stanford University School of Medicine, Palo Alto, California

The long-term use of iodochlorhydroxyquin, 250 mg, 3 times daily, has been employed in 4,000 institutionalized patients over a period of 4 years. Successful prophylaxis against shigellosis and amebiasis was uniformly observed. Successful therapeusis with the same agent against these organisms appears confirmed. Toxic manifestations of such therapy have been extremely infrequent, mild in nature, and completely reversible upon withdrawal of the agent.


* Offered in part at the Annual Meeting of The American Society of Tropical Medicine and Hygiene, November 1963.


{dagger} Public Health Officer, Sonoma State Hospital, Eldridge, California.


{ddagger} Clinical, Associate Professor of Medicine and Director, Endocrine Clinics, Stanford University Medical Center, Palo Alto, California.






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Copyright © 1964 by the American Society of Tropical Medicine and Hygiene.