HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Powell, R. D. Articles by Brewer, G. J. Search for Related Content PubMed PubMed Citation Articles by Powell, R. D. Articles by Brewer, G. J.

Active Immunization Against Malaria^*

Robin D. Powell AND George J. Brewer

Active immunization against malaria is a subject notable for the attention it has not received during the last decade or decade and a half. Early evaluation of the potential of active immunization in man yielded either negative or inconclusive results. During and immediately after World War II, other investigative approaches aimed at combating malaria seemed more promising and were pursued vigorously. Active immunization was relegated a position far in the background.

The introduction of DDT and the development of other effective residual insecticides made possible a new approach to global control of malaria. A new foundation was provided for massive efforts to eradicate malaria by interruption of transmission through the definitive host, the mosquito. In addition, persistent, methodical, and industrious efforts to develop effective chemotherapeutic agents led to some brilliant achievements. Impressive successes that resulted in both the insecticidal and chemotherapeutic fronts took wind out of the sails of malaria research.

^* Part VIII of an International Panel Workshop on the Cultivation of Plasmodia and Immunology of Malaria, Walter Reed Army Institute of Research, Washington, D. C., August 27 and 28, 1963.

Army Medical Research Project of the Department of Medicine, Division of the Biological Sciences, University of Chicago, Chicago, Illinois.