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Am. J. Trop. Med. Hyg., 13(1), 1964, pp. 6-10
Copyright © 1964 by The American Society of Tropical Medicine and Hygiene

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Detection of a Plasmodium Berghei-Antibody Complex Formed in Vivo*

Julius P. Kreier AND Miodrag Ristic
Department of Veterinary Pathology and Hygiene, and the Center for Zoonoses Research, College of Veterinary Medicine, University of Illinois, Urbana, Illinois

Direct staining of Plasmodium berghei with fluorescein-labeled antiserum from infected rodents indicated that these animals are capable of producing an antibody against the parasite. A naturally occurring P. berghei-antibody complex was detected by exposing parasitized erythrocytes from infected mice to fluoresceinlabeled anti-mouse globulin.


* This study was supported in part by grants E-17053Cl and E-3315 from the National Institute of Allergy and Infectious Diseases, U. S. Public Health Service.







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