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Virulence of Different Strains of Trichomonas Vaginalis in the Mouse^*

Strains of Trichomonas vaginalis were isolated from symptomatic patients and normal persons and injected into groups of mice via the intraperitoneal, subcutaneous and intramuscular routes. No relationship was found between the human host status and the virulence of the strain for mice injected intraperitoneally. A possible relationship was observed in mice injected subcutaneously in that the majority of strains isolated from symptomatic patients exhibited more marked virulence for mice than did any of the strains isolated from normal persons. The intramuscular route did not yield data of any value in assessing a possible relationship.

^* This investigation was supported in part by U. S. Public Health Service grant No. E-3593.