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A Case of Apeu Virus Infection

Clarence J. Gibbs, Jr.^*, Evert A. Bruckner AND Steven Schenker

Clinical and virological studies of a case of Apeu arthropod-borne virus infection acquired in the laboratory are described. The virus was isolated from the patient's acute phase serum and was identified by serological methods. Relation of the viral isolate to the illness was supported by development of hemagglutination-inhibiting, complement-fixing, neutralizing and precipitating antibodies to Apeu virus in the patient's convalescent serum.

^* Department of Health, Education and Welfare, Public Health Service, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Arthropod-Borne Virus Section, Laboratory of Tropical Virology, Bethesda 14, Maryland. Present address: National Institute of Neurological Diseases and Blindness, Collaborative and Field Research, Bethesda 14, Maryland.

Present address: Department of Pathology, Peter Bent Brigham Hospital, Boston, Massachusetts.

Department of Health, Education and Welfare, Public Health Service, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Laboratory of Clinical Investigation, Bethesda, Maryland. Present address: Gastric Laboratory, Cincinnati General Hospital, Cincinnati, Ohio.