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Am. J. Trop. Med. Hyg., 12(5), 1963, pp. 815-819
Copyright © 1963 by The American Society of Tropical Medicine and Hygiene

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Histopathology of the Central Nervous System in Swiss Mice Intracerebrally Inoculated with 17-D Strain of Yellow Fever Virus

A. C. Dominguez* AND E. Baruch{dagger}

Adult mice inoculated intracerebrally with a suspension of 17D yellow fever virus were studied by histopathological methods. A myelitis, localized especially in the ventral horns of the lumbar spinal cord, was found. Speculation is made on a possible viral infection through the cerebrospinal fluid, and a similarity with the lesions produced by the poliomyelitis virus in man is pointed out.


* Departamento de Neuropatología, Instituto de Anatomía Patológica, Universidad Central de Venezuela, Caracas, Venezuela.


{dagger} Departamento de Virología, Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Apartado 1827, Caracas, Venezuela.






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Copyright © 1963 by the American Society of Tropical Medicine and Hygiene.