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Am. J. Trop. Med. Hyg., 12(5), 1963, pp. 748-752
Copyright © 1963 by The American Society of Tropical Medicine and Hygiene

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Pathology of Schistosoma Japonicum in the Taiwanese Monkey (Macaca Cyclopis)

I. Comparison of Formosan and Japanese Strains

Virginia L. Swanson* AND James E. Williams
Medical General Laboratory (406), U. S. Army Medical Command, Japan

Nearly equal recovery rates of adult worms from Taiwanese monkeys (Macaca cyclopis) infected with Formosan or Japanese strains of Schistosoma japonicum were recorded. Worm recovery rates from the monkeys were low when comparison was made with the highly susceptible laboratory rabbit, signifying only partial susceptibility. Formosan strain granulomas in the liver contained fewer eggs but were considerably more severe and extensive than Japanese strain granulomas. The possibility that the large, atypical granulomas could be reactions to young, degenerating Formosan worms is discussed. An alternative hypothesis to explain the dissimilar reactions, that Formosan strain eggs are stronger tissue irritants than those of the Japanese strain, is proposed.


* Present address: Pathology Division, U. S. Army Tropical Research Medical Laboratory, San Juan, Puerto Rico.

Address requests for reprints: Medical General Laboratory (406) U. S. Army Medical Command, Japan, APO 343, San Francisco, California.







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