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The Nature of Plasmodium Gallinaceum Host Specificity

I. APPARENT SITE OF SPOROZOITE ARREST IN THE NON-SUSCEPTIBLE SPECIES^*

Under the conditions of the experiments, it appears that sporozoites are not demonstrable in the blood stream of the non-susceptible species up to 1 hour after their deposit by the mosquito in the skin, and only rarely so in that of the susceptible species; that sporozoites survive fully when added to, and incubated in, the whole blood and plasma of the non-susceptible species, but not quite so well in the blood of the susceptible species; and that sporozoites are somehow inactivated practically immediately in the skin of the non-susceptible species when deposited there by the mosquito, though they can be recovered quite well from the site for at least an hour in the susceptible species.

^* This investigation was supported by Research Grant E-3744 from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, and presented at the annual meeting of the American Society of Tropical Medicine and Hygiene, Atlanta, Georgia, 1962.