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Inapparent Infection with Japanese Encephalitis of American Servicemen on Okinawa in 1960^*

W. C. Hsieh, Craig K. Wallace, S. P. Wang AND A. F. Rasmussen, Jr.

Two hundred sixty-one men in a Marine Battalion on Okinawa were studied for the development of hemagglutinin-inhibiting antibodies against Japanese encephalitis virus. Fifty subjects developed hemagglutinin inhibiting antibodies during the summer of 1960. One man had an initial antibody titer of 1/10; this low titer was found to be subsequently increased. During the study period, in none of these 51 men was there any evidence of disease symptoms resembling those due to Japanese encephalitis virus infection. Overt encephalitis was confirmed serologically in one marine from the same Battalion who was not in the study group.

^* This work was supported in part by Contract Nonr 3214(00), Office of Naval Research, and in part by funding under Public Law 480, Section 104(c).

The opinions and assertions contained herein are those of the authors and are not to be construed as official or reflecting the views of the Navy Department or the Naval Service at large.

NAMRU-2 Fellow, 1960-1961, from the Department of Medicine, National Taiwan University, School of Medicine, National Taiwan University, School of Medicine, Taipei, Taiwan.

Visiting Scientist, 1960–1961, NAMRU-2, on sabbatical leave from the Division of Virology, Department of Infectious Diseases, University of California School of Medicine, Los Angeles, California.